Cellartgen is developing “bio-organs”, that are structurally and functionally similar to real organs by taking a multi-discipline approach to organoid culture and advanced biomaterial technologies and applying them to regenerative treatments.
Organoid culture matrices based on propriety decellularization technology can be introduced to improve an organoid culture’s capacity to function and differentiation potential. In addition, microfluidic technology can be utilised to provide both nutrients and gas exchange without damaging organoids and preventing the formation of necrotic cores, allowing for highly functional organoids produced in large numbers.
What is Decellularization?
It is a technology for making high-value biocompatible matrix that removes as much antigens and cellular debris as possible that can trigger an immune response when applied to the body. The matrix made through this technology can be used not only for research but also for clinical cell culture and transplantation.
Organ-specific microenvironments achieved through a decellularized matrix based on decellularization technology not only support the cultivation and differentiation of organoids, but also enhance their capacity to mature and promote self-structuring. By combining these advanced, bioengineered organoids with a biomimetic adhesive technology called Extracellular Matrix (ECM) glue and vascularization-inducing technology, it is ultimately possible to create highly functional bioengineered organs.
What is Bio-mimicry (Nature-inspired)?
Technology inspired by the fundamental structures, functioning principles, and mechanisms observed in nature, these technologies artfully apply these traits to engineering challenges. At it’s core it is an efficient, environmentally friendly, and sustainable core technology made for the future.
Cellartgen’s bio-adhesive hydrogel, introduced through biomimetic technology, is not only highly adhesive but also safe for engraftment. Furthermore, its exceptional adhesive properties, combined with minimal invasiveness, contribute to an extended lifespan of bioengineered organs. This approach maximizes the therapeutic effect when applying regenerative treatments.